American 35 years old collided with a car in ciclaba on the coast of Rimini in Italy on Wednesday.
Hayden suffered “serious brain damage” due to the accident and was placed in a coma medication after a hospital Maurizio Bufalini.
His family, including his mother and his fiance, immediately flew to his side.
The hospital has now confirmed that the former world champion died from his injuries.
Hayden was responsible for the in 2006 for five years the dominance of Valentino Rossi MotoGP ends in what is described as “the most fun season ever seen” man.